Updated
Updated · The New York Times · Sep 3
MD Anderson Study Finds 2 Psilocybin Doses May Prevent Chemo Nerve Damage
Updated
Updated · The New York Times · Sep 3

MD Anderson Study Finds 2 Psilocybin Doses May Prevent Chemo Nerve Damage

3 articles · Updated · The New York Times · Sep 3

Summary

  • Science published MD Anderson research showing two psilocybin doses given before chemotherapy protected mice from peripheral nerve damage, a complication that affects about two-thirds of chemo patients.
  • Six consecutive chemo sessions did not break that protection, which lasted through the study’s eight months and did not alter tumor growth or immune response.
  • Human trials are starting this month, targeting a condition that can cause pain, tingling and numbness severe enough to delay or stop cancer treatment.
  • No effective treatment now exists for chemotherapy-induced neuropathy, which can persist for years after therapy and leaves a large unmet need in cancer care.

Insights

Could a compound in magic mushrooms hold the secret to stopping permanent nerve damage from chemotherapy before it begins?
If non-hallucinogenic psilocybin analogs work equally well, will future cancer patients receive nerve protection without experiencing any psychedelic effects?