Updated
Updated · The Independent · Aug 3
Freenome Wins FDA Clearance for Colorectal Cancer Blood Test in Adults 45 and Older
Updated
Updated · The Independent · Aug 3

Freenome Wins FDA Clearance for Colorectal Cancer Blood Test in Adults 45 and Older

3 articles · Updated · The Independent · Aug 3

Summary

  • SimpleScreen is the second FDA-approved blood test for colorectal cancer screening, targeting average-risk adults 45 and older and returning results within a couple of weeks after a doctor’s office blood draw.
  • More than 48,000 adults were studied, with Freenome saying the test detected about 8 in 10 colorectal cancers and correctly ruled out disease or advanced precancerous lesions in 9 in 10 people.
  • A positive result still requires a follow-up colonoscopy, underscoring that the test is meant to widen screening access rather than replace existing diagnostic procedures.
  • Abbott plans to help launch the test this fall, though pricing has not been disclosed; the only other FDA-cleared rival, Guardant Health’s Shield, was approved in 2024.
  • The approval lands as U.S. colorectal cancer cases rise, with nearly 109,000 new colon cancer cases and close to 50,000 rectal cancer cases expected this year.

Insights

With a low detection rate for precancerous lesions, could this convenient new blood test give patients a dangerous false sense of security?
As colorectal cancer rates rise, will insurance companies eagerly cover this new blood test despite its limitations in preventing the disease?