Doctors say the overall risk remains very low, but they suspect rapid blood-glucose drops and fast weight loss may drive vascular changes; one specialist estimated risk could be about twofold higher in diabetic patients.
Nearly half of patients seeking cosmetic or reconstructive facial surgery at one Houston practice are taking GLP-1s, where physicians are also seeing accelerated facial aging from rapid volume loss.
Specialists stress GLP-1s remain life-saving for many patients and are urging slower, more mindful weight loss and regular follow-up for changes in vision clarity or color perception.