Hebrew University Team Identifies Single-Cell Aging Signature in 112-Reference Study
Updated
Updated · The Jerusalem Post · Aug 1
Hebrew University Team Identifies Single-Cell Aging Signature in 112-Reference Study
3 articles · Updated · The Jerusalem Post · Aug 1
Summary
Researchers at Hebrew University and Hadassah found that aging is uneven cell by cell, with some cells accumulating age-linked changes far faster than neighboring cells.
The study traced that pattern through DNA methylation, identifying a molecular signature at specific genomic sites that marks which cells are biologically older first.
Published in Nature Communications, the work argues scientists should move beyond tissue-wide averages and track the fastest-aging cells inside organs and tissues.
The finding could guide drugs aimed at slowing aging itself and help explain why diseases such as cancer, Alzheimer’s and heart disease become more common with age.