Review of 350 Studies Finds Lower Protein Intake Boosts Metabolism in Sedentary Adults
Updated
Updated · Fox News · Aug 3
Review of 350 Studies Finds Lower Protein Intake Boosts Metabolism in Sedentary Adults
3 articles · Updated · Fox News · Aug 3
Summary
A new review in Cell Press Blue says sedentary adults may gain metabolic benefits by cutting protein rather than calories, offering a potentially easier diet strategy than long-term calorie restriction.
More than 350 studies linked lower protein intake to better metabolism, reduced cellular damage and improved cellular maintenance, with much of the effect tied to a rise in the hormone FGF21.
Researchers said high levels of methionine, isoleucine and valine may keep growth pathways overactive in inactive people, contributing over time to inflammation, weight gain and cellular stress.
The paper does not prove cause and effect in humans, and it says protein needs differ sharply by age and activity level—active people, pregnant women and many older adults still need higher intake.
The findings point toward public health guidance that tailors protein targets to activity level instead of relying on one-size-fits-all recommendations.